Harvest time for CRISPR-Cas?
نویسندگان
چکیده
منابع مشابه
Harvest time for CRISPR-Cas?
The revolutionary gene editing technology CRISPR-Cas is on the verge of widespread application in agriculture, promising easy access to dramatic crop improvements. Companies now licensing the technology face the challenge of regaining the public trust that was lost in the GM debate. Additional insecurity comes from the ongoing patent dispute between two renowned US institutions. Michael Gross r...
متن کاملThe CRISPR/Cas System
The epigenome is a heritable layer of information not encoded in the DNA sequence of the genome, but in chemical modifications of DNA or histones. These chemical modifications, together with transcription factors, operate as spatiotemporal regulators of genome activity. Dissecting epigenome function requires controlled site-specific alteration of epigenetic information. Such control can be obta...
متن کاملSpecial focus CRISPR-Cas
Six years ago a new sophisticated prokaryotic defense system was identified that was termed CRISPR-Cas (CRISPR, clustered regularly interspaced short palindromic repeats; Cas, CRISPR associated). Parts of it, the mysterious repeat sequences, were already detected in 1987 but their function remained unknown for the next 20 y. The CRISPR-Cas system is an adaptive, heritable defense system that pr...
متن کاملCRISPR-Cas: the effective immune systems in the prokaryotes
Approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an RNAi-like pathway. CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems consist of the CRISPR loci with multiple copies of a short repeat sequence separa...
متن کاملA CRISPR / Cas 9 toolbox for
Running title: A CRISPR/Cas9 toolbox for gene editing and transcriptional regulation 1 2 3 Co-corresponding authors: 4 Yiping Qi, Department of Biology, East Carolina University, Greenville, North Carolina 27858; 5 Phone: 252-328-9764; Fax: 252-328-4178, Email: qiy@ecu.edu 6 7 Yong Zhang, Department of Biotechnology, School of Life Sciences and Technology, University 8 of Electronic Science and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2016
ISSN: 0960-9822
DOI: 10.1016/j.cub.2016.10.004